CDME Services yePlasmids - Ind Giredhi
Masevhisi
| CDME Services yePlasmids | ||||
| Mhando | Masevhisi | |||
| Ind giredhi | 1 | Yakazvimirira yakavakirwa ina - Plasmid system |
● Chizvarwa chechitatu China - Plasmid System ● Kanamycin - Kudzivisa Gene ● Kupa rezinesi, kana zvichidikanwa |
● Kutevera zviyero zvekutumira muChina uye US ● yakazara - GMP musangano ● Yakaparadzaniswa nzvimbo yekugadzira mabhangi emasero ● Kuparadzanisa mashopu mukati mevasiri - nzvimbo dzakashata uye dzakashata ● GPM YEMAHARA Management System |
| 2 | GMP chisikwa cheBacterial Cell Bank |
● Kusarudzwa kweMonowl Antibodies ● Nhamba dzakasarudzika dzemabhangi ezvikwereti kuti riiswe ● Cell Bank Kugadziriswa Kwekudzidza |
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| 3 | Maitiro uye bvunzo nzira yekuvandudza |
● Kutevera zvinodiwa purojekiti (pasi pekuchinja kwakarongeka) |
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| 4 | GMP Kugadzira Plasmides |
● Kugadzirwa kwechigadzirwa: 10 mg ~ 1 g (pasi pekuchinja kwakagadziriswa) ● Fermentation vhoriyamu: 3 ~ 30 l (pasi pekushandurwa kwakagadziriswa) ● Nzira yekuchenesa: Vatatu - STEP ANOGADZIRA / TOPS - Nzira Yekupinda |
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| 5 | Kuedza kwepurashi |
● Kuchena (HPLC) ● Kusara e.cli kuongororwa ● Kusara e.cli hcp kuongororwa ● Kusara e.cli rna kuyedza ● Kusara mishonga inorwisa mabhakitiriya ● Simba ● Mycoplasma ● Enyikaxin |
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| 6 | Nzira Inoshanda |
● Nhangariro ● Kurudyi ● Chairo ● Nhasi uye huwandu ● Lod |
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| 7 | Kugadzika Kudzidza |
● refu - kugadzikana kwenguva ● Kugadzika kugadzikana ● Kusimbisa kuongororwa |
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Zvakanakira
| Zvakanakira zvedu Plasmid System:
• Akazvimiririra Akazvimirira Evha - Plasmid System na Kanamycin - Kupikisa Gene • Iyo hurongwa nekugona kwekugadziriswa kwekugadziriswa kwekubhadhara • Kutevedzera marara anoteedzerwa, anoenderana nezvinodiwa, uye anoshanda • Yakawandisa ruzivo mune zvakabudirira Ind Submissions • Car - T Sampuli yekiriniki yekushandisa parizvino inogadzira uye mukushandisa • 2 - 5 mipendero yemapepa epamusoro ekutanga mushure mekushandisa yedu plasmid system kubva mukuenzanisa mumapurojekiti akati wandei |
Zvakanakira zvekugadzira kwedu zvinogadzirwa: • yemahara mishonga inorwisa mabhakitiriya mumiitiro yekugadzira • plasmid kugadzirwa uye kubhengi zvakasikwa mumabhuku ezvipenga • Kuzviparadzanisa kwakazara pakati pevasiri - nzvimbo dzakashata uye dzisina tsvina • kugovera zvigadzirwa zvekupedzisira uchishandisa imwe isolatector • Yakapera CTD madhiri ekurongedza Plasmid Plasmid (yeLentivaram Vector pa3) |
Kugadzira maitiro
Mhando yekudzora
| Bvunzo chinhu | Nzira yekuyedza | |
| Chitarisiko | Kuongorora kwekuona | |
| Kuzivikanwa | Kuzivikanwa 1 | Kudzora Mepu |
| Kuzivikanwa 2 | Sedanger Sequencing | |
| Bvunzo | pH | Nzira 0631 yeChp 2020 |
| Kuchena | Yakakwira performance yemvura chromatography (HPLC) | |
| Residhal E.Coli Host Cell Crotein | Elisa | |
| Rambai E.Coli DNA | q - PCR | |
| Rasaraal e.cli rna | q - PCR | |
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Vakasara mishonga inorwisa mabhakitiriya |
Elisa | |
| Endotoxin | Nzira 1143 ye Chp 2020 | |
| Shuwa | Nzira 1101 yeChp 2020 | |
| Kutsunga kusimba | Dna constration | Nzira 0401 yeChp 2020 |
Purojekiti nguva
Chirongwa cheProjekiti Manage
Hillgene Project Provesment timu, inosanganisira masayendisiti makuru, mamaneja eprojekiti, Project QA uye GPM Nyanzvi, ichaita nhamburiko dzekushanda uye neyakajeka kushanda kwega kwega neGMP.
