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- UYGHUR
Kev Nyaj TCR - T
Keeb kwm txhim kho ntawm TCR - T Cell Kev Kho Mob
Xyoo 2002, Rosenberg pawg neeg yog thawj zaug los nrhiav cov qog - Txawm li cas los xij, nyob rau lwm cov qog, tils yog feem ntau nyuaj kom tau txais thiab siv sijhawm ntev los nthuav hauv vitro. Feem ntau ntawm cov davhlau ya nyob twg sib txawv t cells tom qab nthuav dav, thiab txhawb nqa kev txhawb nqa los tiv thaiv. Hauv cov ntsiab lus no, cov neeg tau tshawb nrhiav seb puas yog tus paub tus kab mob TCR tuaj yeem qhia txog kev kho ntshav ib txwm muaj (PBL) rau kev kho mob, uas yog TCR - t cell kev kho.
Hauv cov txheej txheem txhim kho ntawm TCR - t technology, plaub qhov kev paub tau ntsib:
Thawj tiam ntawm TCR - T raug cais los ntawm T cell ntawm cov neeg mob Vim hais tias ntawm tus naj npawb me ntawm c cell clones thiab loj tus neeg sib txawv, nws yog qhov nyuaj rau kev lag luam.
Lub cim thib ob ntawm TCR - T yog rau clone t hlwb tshwj xeeb tau lees paub los ntawm cov lus TCE antigenically, muab nws TCR cov khoom siv, thiab tom qab ntawd hloov nws mus rau qhov chaw ntawm lub pob zeb. Txoj kev no ua rau muaj kev lag luam ntawm tcr - t tau.
Lub cim thib peb ntawm TCR - T yog txhawm rau txhim kho kev siv tshuaj ntawm TCR - T Los ntawm kev ua kom zoo nkauj rau cov qog, thiab tom qab ntawd transducing nws rau tus neeg mob t hlwb.
Qhov thib plaub - Generation TCR - T yog qhov kev kho mob cell kev sib tw ua rau mob qog, nrog kev txhim kho qog ua kom muaj kev nyab xeeb thiab kev nyab xeeb.
Dab tsi yog TCR - T Cell Kev Kho Mob
TCR - T Cell Kev kho tshuab hluav taws xob - Tus neeg mob kho tau Tell, yog kom paub txog cov qog nqaij hlav thiab ua tiav lub hom phiaj kev kho mob.
