Viral Transduction Enhancer A/B/C (ROU/GMP)

Cat.No. HG-PTD001

Hillgene’s Viral E-hancer series products, as a class of highly efficient and non-cytotoxic lentiviral or retroviral transduction enhancers, are widely used in the viral transduction process of T cells, NK cells and HSC cells based on their unique mechanism of action. Viral E-hancer facilitates the fusion of viruses with cell membranes and the efficient transport of viruses from the plasma membrane to the nucleus after cell entry by decreasing cell membrane viscosity, increasing lipid exchange and transmembrane transport, and transiently regulating the expression of some proteins on the cell surface.

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Overview

Knowledge

Application

·Suitable for transduction enhancement application of viral vectors transducing NK cells, T cells, HSC and other different types of cells.

·Applicable to the transduction-promoting effects of enveloped lentiviruses such as VSVG, BaEV, as well as retroviruses.

·Applicable to the need for reduced virus dosage.

Performance Index

1. Significantly enhance transduction efficiency: Viral E-hancer enhances the efficiency of virus transduction to 2-10 times.

2. Reduce the cost of lentivirus use: Reduce experimental and production costs by effectively reducing the amount of lentivirus required.

3. Enhance safetyEffectively control viral vector copy number (VCN) to ensure compliance with regulatory requirements of FDA, EMA, NMPA and other regulatory agencies.

4. Meet diverse needs: Provide RUO-grade and GMP-grade products to satisfy customers' needs at all stages from R&D to production.

5. Seamless integration into existing processes: detailed instructions are provided for different cell types to ensure easy integration into customers' existing experimental processes and maximize process compatibility.

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