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- UYGHUR
Insight tsheb - t
Kev loj hlob ntawm lub tsheb - T Cell Kev Kho Mob
Kev loj hlob ntawm lub tsheb - Kev kho cell tuaj yeem raug xa rov qab mus rau xyoo 1989, thaum Cross g thiab peb lwm cov kws tshawb fawb ua ntej tau thov lub tswvyim ntawm "tsheb". Tom qab ntawd, nyob rau xyoo 2008, Lub Chaw Futechisis Cancer xub pib ua ntej siv tsheb t hlwb Xyoo 2010, thawj qhov kev vam meej ntawm CD19 - Lub tsheb tsom rau b - Hodgphin lymphoma tau tshaj tawm hauv Tebchaws Meskas. Tom qab ntawd xyoo 2011, Professor Ugl txoj kev kawm ntawm Tsev Kawm Ntawv Mennsylvania tau txais kev txhim kho loj, thiab Emily Lub Tsheb Kho Mob Tseem Ceeb, thiab Kho Mob Lub Tsheb Loj Tau nkag mus rau lub sijhawm tshiab tawg. Nyob rau hauv 2017, Asmeskas Cov Chaw Tswj Xyuas Khoom Noj (FDA) Pom zoo Kev Tso Cai Kev Ua Lag Luam Nyob rau hauv tib lub xyoo, Yescarta, lub tsheb thib ob - Cov khoom siv tshuaj tiv thaiv ntawm tes, tau pom zoo rau kev tso cai ua lag luam. Hauv 2020, FDA pom zoo lub tsheb thib peb t - Cell kho cov khoom Tecartus. Xyoo 2021, FDA pom zoo ob lub tsheb - t hoobplasherapy, breyanzi thiab abeyaing loj b - Hauv tib lub xyoo, CDE los ntawm Tuam Tshoj tseem pom zoo Kev Tso Cai Kev Tso Cai ntawm ob lub tsheb thiab Relma - CEL thiab Recmaet lossis Recrenty Loj B - Cell Lymphoma.
Hauv 2022, FDA pom zoo kev tso lag luam tso cai ntawm carvykti, lub tsheb - t cell kev kho mob antigen (BCMA) rau kev kho mob bell (BCMA) rau kev kho mob bell
Txij ntawm no, lub tsheb t cell kev kho mob tau nkag rau hauv lub sijhawm kho mob qog noj ntshav thiab qhib cov zoo nkauj prelude hauv ntiaj teb.
Dab tsi yog tsheb - T Cell Kev Kho Mob
Tsheb T Cell Kev Kho Mob, tseem hu ua Choj Antigen Recepten Receptor T celli immunotherering uas siv genetic engineering los hloov kho t hlwb hauv vacs. Qhov no tso cai rau lawv qhia tshwj xeeb lees paub cov qog nqaij thiab txhaj cov cell cov hlwb rov qab ua rau tus mob.
