Imoto - T Cell Serum - Ukulungiselela kwamahhala
Imoto - T Cell Serum - Ukulungiselela kwamahhala
✔ Silungele - Ku - Sebenzisa i-lentivirus Nge-Pre - I-MOI e-Titrated (igcina isikhathi se-qc)
✔ Kufaka ne-21 CFR eceleni kwemibhalo engu-11
Ukubuka konke komkhiqizo:
I-serum - Imoto Yamahhala - Ikhithi yokukhiqiza iselula ihlanganisa amamojula amathathu ahlanganisiwe:
T Cell activation & module yokwandisa
T cell basal medium: inikeza izakhi ezibalulekile zesiko le-T cell
I-T Cell Activator: Ihambisa amasiginali we-activation ngokusebenzisa ama-molecule athuthukisiwe akhuthazayo
Imodyuli yokuhlanza iselula
Ubude beMagness - Isistimu ye-Isolation esekwe ku-High - Ukucekelwa phansi kwe-T Cell Trel kusuka kwimikhiqizo ye-Leukarechesis noma i-PBMCS
Imodyuli ye-Car gene TransDulection
Silungele - Ku - Sebenzisa imoto lentivirus
I-Viral TransDument Enhancer (i-Viral E - HanCer B): Ikhulisa ukusebenza kahle kwemoto
Izici ezibalulekile:
Ukuhamba komsebenzi okwenziwe lula kwe-serum - Imoto yamahhala - t Ukukhiqiza
Ikhono lokunwebeka okuphezulu (> 50 - Fold) ngokusebenza okugciniwe (> 90%)
Ukusebenza kahle kweTrankDuction (imvamisa> 60% Car +)
Ukuhlanzeka kweseli okungaguquki (> 95% CD3 +)
Izinja
Ukukhiqizwa kwemoto - t amaseli e-peripheral egazini noma egazini lentambo
Ukuthuthukiswa Kwenqubo: Kusheshisa umugqa wesikhathi futhi kunciphisa izindleko ekuqaleni - Imoto Yesigaba - Ukuthuthukiswa kweTrapy
Ukucaciswa kokusebenza
|
Ipharameter |
Ukucacisa |
|
Ukugoqwa kokwandisa |
> 50x |
|
Ukusebenza kweseli |
> 90% |
|
Ukusebenza kahle kweTransDuction |
> 60% imoto + |
|
T Ukuhlanzeka kweseli |
> 95% CD3 + |
Okuvelele kwedatha:
I-BlueKit® Serum - Imoto yamahhala - Uhlelo lokukhiqiza iselula luhlanganisa amamojula amathathu asebenza ngokusebenza:
I-T cell ukwehlukaniswa nokuhlanzwa
T Ukunwetshwa kwamaselula namasiko
I-CD19 Car gene Transchation
Idatha yokusebenza ebalulekile:
Ifinyelela njalo> ama-98% ubumsulwa kuma-t cell we-t cell (bona umfanekiso)
Igcina ukusebenza okuphezulu (> 95%) kuyo yonke inqubo yokukhiqiza
Inika amandla ukudluliswa kwemoto okusebenzayo (ukusebenza kahle okujwayelekile: 60 - 80%)
Ukusebenza kwenqubo:
Amaseli we-T ahlanzekile (> Ubumsulwa bama-98%) asebesebenze ngokulandelayo kusetshenziswa i-T cell cell futhi wandise ku-T cell ohleliwe ye-T cell basal medium,
Ukuzuza:> 100 - Songa ukunwetshwa,> Ukusebenza kwama-90% esikhathini sonke sesiko
Le module yokwandisa igcina ukuqina kweseli nokusebenza ngenkathi kusekela ukwanda okunamandla.
| Ipharamitha yokusebenza | Ukucacisa |
| Ukumsulwa kweseli ye-nk (%) | > 90% |
| I-CD3 + I-cell residual (%) | <1% |
| I-NK cell Expansion Fold | > 5,000 - Songa |
| Ukusebenza kweseli (%) | > 80% |
Imininingwane yokuthumela
Sinikeza ukuthuthwa okuqandisiwe kuyo yonke imiyalo. Imvamisa, i-oda lakho lizofika ngaphakathi kwe-5 zebhizinisi lebhizinisi e-United States nakwezinsuku eziyi-10 zebhizinisi lakwamanye amazwe. Kodwa-ke, sicela uqaphele ukuthi ukulethwa ezindaweni zasemakhaya kungathatha isikhathi eside.
Isikhathi Sokuhambisa: Ama-oda ajwayele ukucutshungulwa kungakapheli 1 - Izinsuku ezi-3 zebhizinisi. Lapho i-oda lakho selithunyelwe, uzothola i-imeyili yokuqinisekisa ngemininingwane yokulandela.
Imininingwane ebalulekile
Ukucutshungulwa kwe-oda: Ngemuva kokuthi i-oda selikhokhelwe, indawo yethu yokugcina izimpahla idinga isikhathi sokucubungula i-oda lakho. Uzothola isaziso uma i-oda lakho lithunyelwe.
Izikhathi zokulethwa: Ezimweni eziningi, iphakethe lizohanjiswa ngesikhathi esilinganiselwe sokufika. Kodwa-ke, usuku lwangempela lokulethwa lungathinteka amalungiselelo endiza, izimo zezulu, nezinye izinto zangaphandle. Isikhathi sokulethwa kwesikhathi sizoba isikhathi eside kunokujwayelekile kuma-oda afaka ama-preorder noma izinto ezenziwe ngezifiso. Sicela ubheke imininingwane yokulandelela ngosuku olunembile kakhulu lokulethwa.
Izinkinga zokuthumela: Uma uthola ukuthi iphakethe lakho alizange lihanjiswe ngesikhathi esibekiwe; Imininingwane yokulandelela ikhombisa ukuthi iphakethe lihanjisiwe kepha awuyitholanga; Noma iphakheji yakho ifaka izinto ezingekho noma ezingalungile noma ezinye izindaba ze-Logistics, sicela uxhumane nensizakalo yethu yamakhasimende kungakapheli izinsuku eziyi-7 ngosuku lokukhokha ukuze sikwazi ukubhekana nalezi zinkinga ngokushesha.
Ukulandela umkhondo
Lapho i-oda lakho lithunyelwe, uzothola i-imeyili enenombolo yokulandela umkhondo nesixhumanisi sokulandela ukuthunyelwa kwakho.
Ungalandela futhi i-oda lakho ngqo kwiwebhusayithi yethu ngokungena ngemvume ku-akhawunti yakho nokubuka umlando we-oda lakho.
Ukuthumela Imikhawulo
Sicela ugcwalise ikheli lomgwaqo ngokuningiliziwe, hhayi ibhokisi le-PO noma ikheli lezempi (APO). Ngaphandle kwalokho, bekuzodingeka sisebenzise i-EMS ukulethwa (kuhamba kancane kunabanye, kuthatha 1 - izinyanga ezimbili noma isikhathi eside).
Imisebenzi Yamasiko Nenqubomgomo Yentela
Uyacelwa ukuthi uqaphele ukuthi noma yimiphi imisebenzi yamasiko, izintela, noma imali yokungenisa etholwe ngesikhathi sokuthumela kungumsebenzi womthengi. Lawa macala ayahluka ngokuya ngezwe elikuyo futhi anqunywa yiziphathimandla zendawo.
Ngokuthenga kusuka kuwebhusayithi yethu, uyavuma ukukhokha noma yimiphi imisebenzi esebenzayo noma izintela ezihambisana ne-oda lakho. Asinacala ngokubambezeleka okubangelwa imvume yenkambiso.
Inqubomgomo ye-Pickup Package
Lapho i-oda lakho selifikile endaweni ekhethiwe ye-pickup noma indawo yokulethwa, sicela uqinisekise ukuqoqwa okusheshayo. Uma iphakethe lingathathwanga ngaphakathi kwesikhathi esibekiwe, sizothumela isikhumbuzi nge-imeyili noma nge-SMS. Kodwa-ke, uma iphakethe lingaqoqwanga esikhathini esibekiwe, futhi noma yikuphi ukulahleka noma ukulimala kwenzeka ngenxa yalokho, umthengi uzoba nesibopho. Sikukhumbuza ngomusa ukuthi uqoqe iphakethe lakho ngokushesha ukugwema noma yiziphi izingqinamba ezingaba khona.
Qaphela: Njengoba umkhiqizo wethu uwela ngaphansi kwesigaba esikhethekile, ukubuyiselwa kwemali kanye nokubuyiselwa kwemali akwamukelwa.
