Imoto - T selfium - Ikhithi yokulungisa i-Shift
Imoto - T selfium - Ikhithi yokulungisa i-Shift
✔Ilungile - I-LITE Ngaphambi kwexesha - I-Moited moi (igcina ixesha le-qc)
✔Ibandakanya i-21 cfr icandelo le-11 amaxwebhu
Amagqabantshintshi eMveliso:
I-serum - Imoto yasimahla - I-t seseli yemigangatho yeseli iquka iimodyuli ezintathu ezihlanganisiweyo:
Imodyuli yefowuni kunye nemodyuli yokwandiswa
I-TWIAL Pepeal Peedium: ibonelela ngezakha-mzimba ezibalulekileyo kwinkcubeko ye-T
I-Argacitor yeseli: Ukuhambisa imiqondiso yokuvula kwiimolekyuli ezifanelekileyo
Imodyuli yokuCoca yeseli
I-Beagnetic Bead - Inkqubo esekwe yedwa yeNdlela eNgcwele - Ukucoceka kweSeli yeSeli kwi-lekaPheres yeemveliso ze-lekaPheress okanye ii-PBMCs
Imodyuli yokutshixwa kwemoto
Ilungele - Ukusebenzisa i-lenthivirus yemoto
I-Viral Translations Iyondisi (i-Viral E - I-hancer b): Ukunyusa ukudityaniswa kwemoto
Ezona mpawu:
Imowudi yokuhamba kweShoum - Imoto yasimahla - t Imveliso
Amandla aphezulu okukhula (> 50 - Songa) ngokugcinwa kokusebenza (> iipesenti ezingama-90)
Ukutshintshela okuphezulu kokusebenza (ngokwesiqhelo> I-60% yemoto +)
Ukucoceka okungaguqukiyo kwe-T) (> I-95% ye-CD3 +)
Izicelo
Ukuveliswa kwemoto - Iiseli ze-T kwigazi le-peripheral okanye igazi lentambo
Ukuphuhliswa kwenkqubo: Ukukhawulezisa i-titeline kwaye kunciphisa iindleko zokuqala - I-TARD yeSigaba - T Uphuhliso Lonyango
Inkcazo yokusebenza
|
Iparameter |
Ukucaciswa |
|
Isongelelo |
> 50x |
|
Ukusebenza kweseli |
> Iipesenti ezingama-90 |
|
Ukutshintsha kokusebenza kakuhle |
> I-60% yemoto + |
|
T Ukucoceka kwesesi |
> I-95% ye-CD3 + |
IiDayithi zeDatha:
I-Bluum ye-Bluum - Imoto yasimahla - I-T Seline yokuFumanisa idibanisa iimodyuli ezintathu ezisebenzayo:
I-T Sele Courating kunye nokuCoca
Ukukhula kweseli nenkcubeko
I-CD19 i-Geen Transloction
Idatha yeNtsebenzo eziphambili:
Ukungaguquguquki rhoqo
Gcina ukusebenza nzima (> i-95%) kuyo yonke inkqubo yokuphuhlisa
Yenza ukutshintshelwa kwemoto efanelekileyo (ukusebenza kakuhle: 60 - 80%)
Inkqubo yokuSebenza:
Iiseli ze-T ezihlanjululwe (> 98% ukucoceka) zivuliwe emva koko kusetyenziswa i-Acced ye-T selokishi kwaye yandiswa kwiseli ye-TWIAL ESIPOL,
Ukufezekiswa:> I-100 - Ukugoba kwe-100 - I-SORTALY,> I-90% yeMisebenzi kuyo yonke ixesha lenkcubeko
Le modyuli yolwandiso igcina ukungabi nasemzimbeni wesel kunye nokusebenza ngelixa ixhasa ukwenziwa kwesahlulo esomeleleyo.
| Ipharamitha yokusebenza | Ukucaciswa |
| I-NK ucoceko lweseli (%) | > Iipesenti ezingama-90 |
| I-CD3 + Iseli entsalela ye-CD3 (%) | <1% |
| I-NK ye-NK | > I-5,000 - Songa |
| Ukusebenza kweseli (%) | > Iipesenti ezingama-80 |
Ulwazi lokuhambisa
Sinikezela ngothutho oluhlaziyiweyo kuyo yonke imiyalelo. Ngokwesiqhelo, iodolo yakho iya kufika ngaphakathi kwe-5 - Iintsuku ezisi-7 zeshishini eUnited States kwaye kwiintsuku ezili-10 zomsebenzi wamazinye amazwe. Nangona kunjalo, nceda uqaphele ukuba ukuhanjiswa kweendawo ezisemaphandleni kunokuthatha ixesha elide.
Ixesha lokuhambisa: Ii-odolo zihlala zisetyenzwa ngaphakathi 1 - iintsuku ezintathu zomsebenzi. Nje ukuba i-odolo yakho ithunyelwe, uyakufumana i-imeyile yokuqinisekisa ngolwazi lokulandela umkhondo.
Ulwazi olubalulekileyo
Ukuqhubekeka kocwangco: Emva kokuba i-odolo ihlawulwe, i-Warehouse yethu idinga ixesha lokuqhuba iodolo yakho. Uya kufumana isaziso emva kokuba i-odolo yakho ithunyelwe.
Amaxesha okuhambisa: Kwiimeko ezininzi, iphakheji iya kusiwa ngexesha eliqikelelweyo lokufika. Nangona kunjalo, umhla wokwenyani unokuchaphazeleka ngamalungiselelo eenqwelomoya, iimeko zemozulu, kunye nezinye izinto zangaphandle. Ixesha lokuhanjiswa kwexesha liya kuba ngaphezulu kwesiqhelo semiyalelo ebandakanya ukhuseleko okanye izinto ezenziwe ngokwezifiso. Nceda ujonge ulwazi lokulandelela ngowona mhla uchanekileyo wokuhanjiswa.
Imicimbi yokuhambisa: Ukuba ufumanisa ukuba iphakheji yakho ayihanjiswanga ngexesha elimiselweyo; Ulwazi lokulandela umkhondo lubonisa ukuba iphakheji ihanjisiwe kodwa awukayifumani; Okanye iphakheji yakho ibandakanya izinto ezilahlekileyo okanye ezingachanekanga okanye eminye imiba yempahla, nceda uqhagamshelane nenkonzo yethu yabathengi kwiintsuku ezisi-7 zomhla wokuhlawula ukuze sikwazi ukujongana nale micimbi ngokukhawuleza.
Ukulandelela umkhondo
Nje ukuba i-odolo yakho ithunyelwe, uyakufumana i-imeyile ngenombolo yokulandela umkhondo kunye nekhonkco lokulandelela ukuthunyelwa kwakho.
Unokulandelela i-odolo yakho ngqo kwiwebhusayithi yethu ngokungena kwiakhawunti yakho kwaye ujonge imbali yakho ye-oda.
Izithintelo zokuhambisa
Nceda ugcwalise idilesi yesitrato ngokweenkcukacha, hayi ibhokisi ye-PO okanye idilesi yomkhosi (AP). Ngaphandle koko, kuya kufuneka sisebenzise i-EMS yokuhanjiswa (ihamba kancinci kunabanye, ukuthatha malunga 1 - iiyure ezi-2 okanye ixesha elide).
Imisebenzi yesiko kunye nomgaqo-nkqubo werhafu
Nceda uqaphele ukuba nayiphi na imisebenzi yesiko, irhafu, okanye intlawulo yokungenisa okwenziweyo ngexesha lokuhambisa luxanduva lomthengi. Ezi ntlawulo ziyahluka ngokuxhomekeke kwilizwe eliya kulo kwaye zimiselwa ngabasemagunyeni basekhaya.
Ngokuthenga kwiwebhusayithi yethu, uyavuma ukuhlawula nayiphi na imisebenzi esebenzayo okanye irhafu enxulumene ne-oda yakho. Asinaxanduva lokulibaziseka okubangelwa kukucocwa kwesiko.
Umgaqo-nkqubo wePakeji yephakheji
Nje ukuba i-odolo yakho ifikile kwindawo echongiweyo yePickup okanye indawo yokuHanjiswa, nceda uqinisekise ukuqokelelwa ngokukhawuleza. Ukuba iphakheji ayithanga ngexesha elichongiweyo, siya kuthumela isikhumbuzo nge-imeyile okanye nge-SMS. Nangona kunjalo, ukuba iphakheji ayiqokelelwa ngaphakathi kwexesha elichaziweyo, kwaye nayiphi na ilahleko okanye umonakalo ovela ngenxa yoko, umthengi uya kuba noxanduva. Ngobubele kukhumbuza ukuba uqokelele iphakheji yakho ngokukhawuleza ukuphepha nayiphi na imiba enokubakho.
Qaphela: Njengoko imveliso yethu iwela phantsi kodidi olukhethekileyo, ibuyise kunye nokubuyiselwa kwemali ayamkelwa.
