I-Glycoera iphakamisa i-130m ye-130m, inzala enomdla kwi-proproders

I-biotechnolom ye-biotechnolom iphuhlisa amachiza owalelwe ekupheliseni iiproteni ezinobuchule ezifunyenwe ngaphandle kweeseli zinyuse i- $ 130 yezigidi ukuqala ngelingweni lekliniki yokuqala.

Ukuqala, i-Glycoera, iya kusebenzisa uthotho lwe-B ukuvelisa idatha yokuqala yeklinikhi yenkqubo yayo ekhokelayo, unyango lwefomuni lomzimba lwe-ge8820. Inenjongo yokuzisa ichiza lesibini lomzimba liye kuvavanyo lomntu.

I-Glycoera Veew Ge8820 njengohlobo lwamandla ngokubanzi anokwenza ukuba "ngumbhobho kwimveliso yenkampani kunye ne-CEO Ganesh Kaundinya. I-STIONGETY ijolise kwi-Igg4, ukujikeleza i-antids enokukhusela i-allergies, kodwa ukungasebenzi kakuhle kwaye kuhlasela izicubu zakho zomzimba ngaphakathi Iimeko ezininzi ze-autoimmune, phakathi kwabo isikhumba esikhuselweyo se-pempphigus kunye nemo yesamente ye-Kisney.

I-GE8820 yindawo yokuhlala Inxalenye enye yemolekyuli ibopha kwi-antidy kwaye ityhila esibindini. Elinye icala emva koko laatptor kwi-igitw efumana i-Igg4 kwiiseli, apho ithethwe yiproteni yangaphakathi - Inkqubo yokulahla inkunkuma.

Ngokuka-Glycoera, uvavanyo oluchanekileyo lubonakalisile ukuba le ndlela inokususa ukungasebenzi kakuhle i-Igg4 Antibodies ngohlobo lokuchaneka olungabonwa ngezinye iindlela. Ngokwenza njalo, i-GE8820 ingayiphepha imiphumo yobuntu ngokubanzi yamayeza amanye amayeza aManyano. Isenokuphelisa "umthwalo kwinkqubo yezempilo, utshilo uKaundinya.

Izigulana zihlala "zinyangwa, ziba ngcono, zilungile, kwaye emva koko babuyele emva koko," utshilo uKaundinya. "Indlela yethu ayiyonzi nje ukuba izigulana ziphile ubomi obungcono, nayo iyonke inegalelo kwiBhodi yezeMpilo kwiBhodi."

I-Glycoera ichaze esidlangalaleni iinkqubo ezintathu ezingemva kwe-ge8820, kodwa ayichazi ukuba ziphi izifo ezijolise kuzo. Inkampani inokungenisa isicelo sokuqalisa izilingo zechiza lesibini ngonyaka wama-2026, Ngokwewebhusayithi yayo. 

I-Hovo Doldings ikhokelele uthotho lukaGlycoera b Ringe, obandakanya iingalo ze-roure ze-roche kunye ne-bristol ye-curibb, amaqabane eSofnnova kunye nezinye iifemu ezininzi.

"Eyona nto iphume ngayo nge-Glycoera kukuba ubunetyala elisetyenzisiweyo apha, kwizifo ezinesifo sika-Autoimmune, inani eliphezulu lezinto zonyango kunye ne-ratiologings ye-UNvoings i-UNEX HARYIDS HARD. "Njengoko sibona isithuba sezifo ze-autoimmunine eguqukayo, iyeza elichanekileyo le-Glycoera liza kuza kumphambili."

I-Glycoera ibizwa emva kwe-GlycosyItrong, inkqubo apho kukho imixokelelwane yeswekile eqhotyoshelwe kwiproteni. Inkampani yenzelwe i-Wädenswil, iSwitzerland kwaye inonyawo lwe-U.S. Yayingempela ye-Swiss biotech Limmatech Biologics kwi NgoJanuwari 2021, kwaye ukhulisiwe malunga ne-49 yezigidi Kwinkxaso-mali yenkxaso-mali ye-Novemba.

Umjikelo wenkampani wakutshanje ubungqina obuqhubekayo bokuqhubeka inza inzala ngoko - Iiprotein ezibizwa ngokuba ziiprotein zeProneein, ezibonelela ngendlela yokufikelela kwiiproteni zeeproteni azifikeleli. Uphando malunga nokupheliswa kweprotein khutshiwe ukusukela oko jika kwinkulungwane, ukuvumela uluhlu lweenkampani ezisebenzisayo Iindlela ezahlukeneyo ukuya Ukutshabalalisa iiproteni eziyingozi.

Phawula:Iphinde yafunyanwa kwi-biophaphadive. Ukuba kukho nakuphi na inkxalabo yelungelo lokushicilela, nceda uqhagamshelane neqela lewebhusayithi ukuze zisuswe.