Ibinyabuzima bitangira guteza imiti igamije gukuraho poroteyine zifite ibibazo iboneka hanze ya selile zambutse miliyoni 130 zo gutangiza urubanza rwarwo rwa mbere.
Gutangira, Glycoera, bizakoresha urukurikirane rw b amafaranga yo kubyara amakuru yambere kuri gahunda yayo yo kuyobora, kwivuza indwara idakingiwe yiswe Ge8820. Irateganya kuzana ibiyobyabwenge bya kabiri kubigerageza byabantu.
Glycoera Reba Ge8820 nko kugira ubwoko bwagushoboka bwagutse bishobora gutuma "umuyoboro wa Ganesh. Ibiyobyabwenge byibiyobyabwenge Igg4, antibody yazengurutse ishobora kurinda allergie, ariko imikorere mibi kandi yibasira ingirangingo z'umubiri muri Imiterere myinshi ya autoimMune, muri bo guhungabanya uruhu rwa Pemphigus hamwe nimpyiko zisabwa membranous nephropathy.
Ge8820 nibiri - Ibiyobyabwenge bikora bihambira umubiri gusenya iyi Igg4 ifite inenge. Igice kimwe cya molecule gihuza na antibody kandi kikurura umwijima. Ikindi gice icyo gihe kirashira mu ruganda rukurura igg4 mu tugari, aho bimaze gutabwa na poroteyin y'imbere - sisitemu yo kujugunya.
Dukurikije Glycoera, ikizamini cyibanze cyerekanye uburyo bushobora gukuraho igenamisi rikora igg4 hamwe nubwoko bwumuntu butagaragara hamwe nubundi buryo. Nubikora, Ge88820 hashobora kwirinda ingaruka nini ya Immunosuppressive yindi miti ya automune. Kaundinya yavuze ko birashobora kandi koroshya "umutwaro kuri gahunda yubuzima." Kaundinya.
Kaundinya yagize ati: "Bavuwe, bakira neza, bameze neza, hanyuma bagaruka kuri iyo bagasubiramo." Ati: "Uburyo bwacu bwo kubaho gusa abarwayi kubaho neza, muri rusange bigira uruhare mu nshipino myiza y'ubuvuzi."
Glycoera yatangaye ku mugaragaro izindi gahunda eshatu zinyuma ya Ge8820, ariko ntiyigeze zigaragaza indwara zibatera. Isosiyete irashobora gutanga icyifuzo cyo gutangira ibigeragezo kubiyobyabwenge bya kabiri muri 2026, Ukurikije urubuga rwarwo.
Novo Caldings yayoboye urukurikirane rwa Glycoera B kuzenguruka B impande zose za Rothe na Bristol Myers Squibb, abafatanyabikorwa ba Sofinnova ndetse n'ibindi bigo byinshi.
No. gufata umufatanyabikorwa mukuru, Novo akorana na mugenzi wawe KEXOMS, Umufatanyabikorwa mu binyabuzima akomeye kandi ashimangira rwose. " Ati: "Nkuko tubibona indwara ya automune Umwanya urahinduka, abakora ubuvuzi bwa Glycoera bagiye kuza ku isonga."
Glycoera yitiriwe Glycosylation, inzira yiminyururu isukari yometse kuri poroteyine. Isosiyete ifite icyicaro i WädenWil, mu Busuwisi kandi ifite Ikirenge cya Amerika muri Newton, Massachusetts. Byari kuzungura mu bikoresho byo mu Busuwisi Litech Limmatech biologique muri Mutarama 2021, kandi yazamutse hafi miliyoni 49 z'amadolari Mu rukurikirane rw'inkunga yo mu Gushyingo.
Uruziga ruheruka ni ikindi kimenyetso cyerekana ko ukomeje gushishoza muri iki gihe - Byitwa Producers, itanga uburyo bwo kujya muri poroteyine uburyo bwo gukoresha ibiyobyabwenge budashobora kugeraho. Ubushakashatsi muri proteine yakuyeho kuva hindukirira ikinyejana, gutanga umurongo wibigo ukoresheje Uburyo butandukanye Kuri gusenya poroteyine zangiza.
Icyitonderwa:Yasubiwemo kuva kuri ibinyabuzima. Niba hari impungenge zuburenganzira, nyamuneka hamagara ikipe y'urubuga kugirango ikureho.
Igihe cyagenwe: 2025 - 05 - 30:23:56
