Glycoera- Txog $ 130M, caij cov paj laum hauv cov protein degradaders

Pom cov tshuaj muaj teeb meem tsim los ua cov protein uas muaj teeb meem sab nraum lub hlwb tau tsa $ 130 lab los pib nws thawj lub chaw kuaj mob.

Lub sijhawm pib, glycoera, yuav siv cov ntaub ntawv beries los tsim cov ntaub ntawv kho mob thawj zaug rau nws cov kev pabcuam coj ua, tshuaj tiv thaiv kab mob tsis muaj mob dubbed Ge8820. Nws npaj yuav nqa ib qho tshuaj tiv thaiv kab mob thib ob rau tib neeg kev sim ib yam nkaus.


Glycoera Views Ge8820 raws li muaj hom muaj peev xwm dav uas tuaj yeem ua rau nws yog qhov chaw ua haujlwm ntawm cov khoom lag luam, "CEO Ganesh Kaundinya. Lub hom phiaj siv tshuaj igg4, ib cheeb tsam kev tiv thaiv kev tiv thaiv uas tuaj yeem tiv thaiv kev ua xua, tab sis malfunctions thiab tawm tsam lub cev nqaij hauv Muaj ntau cov xwm txheej autoimmune, ntawm lawv cov tawv nqaij tsis zoo thiab lub raum xwm txheej thawj lub membranous Memotropathy.


Ge8820 yog dual - ua yeeb tshuaj uas coaxes lub cev mus rau kev rhuav tshem cov tsis haum no igg4. Ib feem ntawm cov molecule khi rau cov tshuaj tiv thaiv thiab rub nws mus rau daim siab. Lwm feem ces latches mus rau lub receptor uas nqus iigg4 rau hauv cov hlwb, qhov twg nws tau khib nyiab los ntawm cov protein - pov tseg.

Raws li Glycoera, kev sim ua ntej tau qhia tau txoj hauv kev tuaj yeem tshem tawm igg4 cov tshuaj tiv thaiv nrog hom precision tsis tau pom nrog lwm txoj hauv kev. Los ntawm kev ua li ntawd, Ge8820 yuav zam tsis txhob muaj kev tiv thaiv dav dav ntawm lwm cov tshuaj autoimmune. Nws kuj tseem yuav tau qhov "nra hnyav rau kev kho mob," Kaundinya tau hais.


Cov neeg mob feem ntau "tau kho, lawv tau txais kev zoo dua, lawv zoo, thiab tom qab ntawd lawv rov qab los rov qab los. "Peb txoj hauv kev tsis tsuas yog ua rau cov neeg mob ua lub neej zoo dua qub, nws tseem muaj kev sib tw ua rau muaj kev lag luam kho mob zoo dua."


Glycoer tau tshaj tawm txog peb lwm cov haujlwm tom qab Ge8820, tab sis tsis tau teev cov tshuaj uas lawv tau mob. Lub tuam txhab tuaj yeem xa cov lus thov los pib sim rau nws cov tshuaj thib ob hauv 2026, Raws li nws lub vev xaib

NOVE LEDMS LED Glycoer B round, uas koom tes nrog kev lag luam caj npab ntawm Roche thiab BRistol cov neeg koom tes thiab ntau lwm cov tuam txhab.


"Dab tsi yeej sawv nrog Glycoera yog koj tau muaj kev sib tw ntawm tus kab mob pib, muaj cov kev sib tw autoimmune yog qhov muaj zog heev," "Thaum peb pom cov kab mob autoimmune thaj chaw hloov kho, cov tshuaj kho mob xws li glycoera yuav los mus rau tom ntej."


Glycoera muaj npe tom qab glycosylation, cov txheej txheem los ntawm cov suab thaj uas txuas nrog cov protein. Lub tuam txhab yog lub tsev nyob hauv Wädenswil, Switzerland thiab muaj U.S. Hneev hauv Newton, Massachusetts. Nws tau spun tawm ntawm Swiss Biotech Limmatech Biologics hauv Lub Ib Hlis 2021, thiab tsa kwv yees li $ 49 lab Hauv cov nyiaj hauv cov nyiaj xyoo lub Kaum Ib Hlis.


Lub tuam txhab kev sib tw tshiab tshaj plaws yog cov pov thawj ntxiv ntawm kev nyiam txuas ntxiv hauv yog li - tau hu ua cov protein ib txwm muaj kev siv tshuaj yeeb tshuaj tsis ncav cuag. Tshawb nrhiav rau cov protein degradation tau coj tawm txij li lub tig ntawm lub xyoo pua, yielding ib qho array ntawm cov tuam txhab siv Cov Qauv Sib Txawv rau Ua kom puas cov protein.

Nco tseg:Rov qab los ntawm misharmadive. Yog tias muaj kev txhawj xeeb txog kev cai

 


Lub sij hawm Post: 2025 - 05 - 30 11:2:56
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