I-Biophapharmaceutical R & D ijongene noxinzelelo ngakumbi kunangaphambili. Iinkampani kulindeleke ukuba zikhawulezise isantya sezinto ezintsha, ukunciphisa amaxesha abekiweyo, kunye nokulawula iindleko zokuxolelwa-zonke ngelixa uhambahamba ngesayensi eyandayo. Namhlanje, ithatha iminyaka eli-10 ukuya kweli-15 kwaye ukuya kuthi ga kwi-2,6 yezigidigidi ukuzisa ichiza elinye kwimakethi, kunye namazinga empumelelo ajongene ne-12%. Kule - Umngcipheko, ophakame - imeko engqongileyo, inyanzelisa indlela ezenza ngayo isayensi.
Ukuhlangabezana nezi mfuno, iinkokeli ze-biopharma ziyicingela iziseko zazo zedijithali. Iqonga lemigangatho ehlanganisiweyo ye-Allics La maqonga anikezela ngendlela enobuchule, engaphezulu edibeneyo yokulawula idatha, ukunkcenkceshela okwenziwayo, nokuxhobisa amaqela ukwenzela izigqibo ngokukhawuleza, ukuzithemba ngakumbi.
Iindleko ezifihlakeleyo zezixhobo ezinqahliweyo
Ngaphandle kwenkqubela phambili ekuqokeleleni idatha, uninzi lweelebhu namhlanje zixhomekeke kwiinkqubo eziqhekekileyo zokuxhasa uphando lwemihla ngemihla. Imilimi (iinkqubo zolawulo lweelebhu), i-ELS (iincwadana zeLebhu yeLebhu yeLebhu), kunye nezixhobo zohlalutyo zihlala zikhona kwi-silos, nganye yenzelwe umsebenzi othile. Kodwa ngaphandle kokudityaniswa okungenamthungo, ezi nkqubo zenza iingxaki ezingaphezulu kunezo zisombululayo.
Ukuchaneka, ukudityaniswa okungenamthungo kubhekisa ekudibaniseni iinkqubo ezininzi zesoftware okanye izinto ngendlela yokuba idatha ihamba ngokuzenzekelayo kwaye ngokuchanekileyo, abasebenzisi bafumana isiphelo sendlela yokungenelela, kunye notshintsho olubonakalayo phakathi kweenkqubo. Oku kuthelekiswa nokudityaniswa kwengxowa-mali, edla ngokubandakanya i-Disos yedatha enqunyalisiweyo, i-intermas engahambelaniyo, kunye neencwadana ezinesandla phakathi kwamanqanaba okubetha komsebenzi.
Izazinzulu zihlala zihlala zichitha i-15-25% yexesha labo lokudlulisela idatha phakathi kwamaqonga. Le nzame ingenisa ukulibaziseka okungafunekiyo kwaye yonyusa ukubakho kwempazamo yempazamo yomntu ye-5-5% ayiyonto ingaqhelekanga ngexesha lokuthumela ngesandla. Ezi mpazamo, nangona zihlala zincinci, zinokwenza indawo yokuhambahamba komsebenzi kunye nokwazisa ukwahluka okuzithemba kwiziphumo.
Ngaphaya kokuchaneka, ukwahlulwa kukwabangela ukulibaziseka kwisigqibo - Ukwenza. Idatha edibeneyo evela kwizixhobo ezikhutshiweyo iyongeza umyinge weeveki ezintathu ukuya kwezine kwi-special Special, inkqubela phambili kwinqanaba ngalinye. Iqela elilawulayo elizama ukuhambisa imijikelezo yophuhliso okanye iphendule kumathuba asakhulayo, ezi ukungasebenzi kakuhle zibonisa umqobo omkhulu.
Ixabiso lenzululwazi lokudityaniswa
Iqonga lemigangatho ehlanganisiweyo Idilesi yemingeni ngokudibanisa idatha, izixhobo kunye namaqela. Izibonelelo zihamba ngaphaya ngokulula - ziya kuphucula umgangatho wesayensi, ukukhawulezisa amaxesha abekiweyo, kwaye unciphise umngcipheko wokusebenza. Nazi ezintathu zezona zibonelelo zibalulekileyo:
1. Ukuphuculwa kwedatha yedatha esebenzayo
Iinkqubo ezihlanganisiweyo ezenzekelayo ezenzekelayo ezininzi zetsheki ukuba izazinzulu zikhe zenze ngesandla. Yakhiwe - Ukuqinisekiswa kwe-Algorithms eqinisekisiweyo Qinisekisa ukuchaneka kwedatha, iitsheki, kunye nezinye iindlela zobuchule, ukunciphisa ixesha elifunekayo kulawulo lwenqanaba lomgangatho. La maqonga agcina iindlela zophicotho-zincwadi ezizeleyo, ukufaka ulwazi ngokwemeko njengesixhobo sokulinganisa, iRegent Amanani kaninzi, kunye neemeko zovavanyo. Oku kudala irekhodi elibanzi lomsebenzi wesayensi oluxhasa ukuthotyelwa kwemigaqo efana ne-21 cfr icandelo le-11 kwaye wenze lula uphicotho oluzayo okanye uphando.
Ukugcina ixesha kubalulekile: Amaxesha okuqinisekiswa kwamaxesha okuqinisekiswa ancitshiswa nge-60-70%, ekhulula izazinzulu kunye namaqela e-QBA ukugxila kumsebenzi ophezulu.
2. Ukukhawuleza kunye nendlela ethembekileyo yokudluliselwa
Indlela yokudluliselwa phakathi kwee-labs-ngakumbi ngexesha lezika - phezulu okanye kade - uphuhliso lwenqanaba-ihlala ibhotile. Iindlela zesintu zinokuthatha iinyanga, zifuna amaqela ukuba ahlaziye iiprothokholi eziPhakathi kwaye aphucule idatha exhasayo. Iqonga elihlanganisiweyo lenze lula le nkqubo ngokubonelela ngemigangatho yokudluliselwa kweekhilomitha kunye nokufikelela kwiinkqubo eziqinisekisiweyo. Ngenxa yoko, amaxesha okudluliselwa kwendlela ahlala enqunyulwa kwisiqingatha, evumela uthungelwano olukhoyo phakathi kwamasebe kunye nokuqhubela phambili ngokukhawuleza ngombhobho wophuhliso.
I-3. Uhlalutyo lobuchule kwi-AI yeSayensi
Iqonga lale mihla lenza ukuba uhlalutyo oluphezulu ngakumbi ngokubandakanya ubukrelekrele bobukrelekrele kunye nokufunda koomatshini okhethiweyo kwiimfuno ezizodwa zophando lweyeza. Ukufunyanwa kweziyobisi kubandakanya i-datasets engalinganiyo, apho i-comples esebenzayo ihluthwe kakhulu ngabasebenzi. Ngokubanzi - Injongo ye-AI izabalazela kwezi meko, kodwa isayensi - I-algorithms eyaziyo inokuthi ibonwe ukuba ifumane iipateni ezinqabileyo kodwa ezibalulekileyo, kunye neSigqibo seSikhokelo - Ukwenza ukufunyanwa kwesikhokelo kunye nokukhokela kwangoko. Obo buchule buvumela amaqela ukuya kuqonda ngaphezulu kwengqondo enokuthi ilahlekelwe kwingxolo.
Iziphumo eziqinisekisiweyo ebaleni
Impembelelo yokudityaniswa ayisiyo nje i-theoretical. Izifundo zetyala zibonakalisile ukuba amaqonga ezi-Alliestats ahlanganisiweyo anokuphucula kakhulu ukusebenza kwe-R & D D.
Kwi Unyango lwe-ptc, ukumiliselwa okudityanisiweyo Imilimbo Iqonga le-ELN leMfundo lanceda ukulungelelanisa iinkqubo ezincinci kunye neemolekyuli ezinkulu. Oku kungekuphela nje umnqamlezo ophuculweyo kuphela - Intsebenziswano kodwa ikwancede ukulandela umkhondo okhethekileyo kwaye kuhlalutyo lwedatha, i-dattal yedatha, ihla i-silos esele inciphise inkqubela phambili.
Eminye imibutho inika ingxelo yoko Iincwadana ezinemifanekiso edityanisiweyo zeLebhu Ukunyusa ukusebenza nge-15-25% kwi-biology ye-biology-obukhulu ngaphezu kokufumana imali ebonakalayo kwi-chemistry - iinkqubo ezigxile kuzo. Olu phuculo luguqulela ngokuthe ngqo kwibhentshi yebhentshi yezazinzulu kunye nexesha elincinci elichithwe kumaxwebhu ethululo okanye i-datarling.
Ityala lezemali lokudityaniswa
Ukusuka kwimbono yemali, amaqonga ahlanganisiweyo ahlanganisiweyo ahambisa imbuyekezo eqinileyo. Buyela kwimodeli yotyalo-mali (i-ROI) esekwe kwixabiso elikhoyo ngoku, i-NPV), ukuhamba kwemali, kwaye ubungozi bubonisa ukuba iimveliso zemveliso zinokucacisa utyalomali. Kodwa ixabiso lokwenyani landise ngakumbi kumgangatho wedatha ophuculweyo, ukungeniswa kwemigaqo esebenzayo, kunye nokuncitshiswa kokuncitshiswa kokuthotyelwa okanye ukulahleka kwedatha.
Ukujonga phambili: indlela yengqondo yokufumanisa
Ukutshintsha kwe-conmatics ezihlanganisiweyo kubonisa utshintsho olubanzi kwindlela imibutho ye-bibpharma isebenza ngayo. Yinto eshukumayo evela kwi-projective, i-curbledsflow ye-project kwinkqubela phambili, idatha - ISAYENSI. Abaphathi abazamkela le tshintsho babeka ngokukhawuleza imibutho ukuba bakhawuleze, banobuchule, kwaye basebenze ngakumbi kwimarike yokhuphiswano nenguqu.
Ekugqibeleni, ukudityaniswa akusekho malunga nokongeza itekhnoloji engaphezulu-imalunga nokususa uxinzelelo olucothayo kwiSayensi enkulu. Ngokutyalomali kumaqonga ahlanganisweyo, iinkokeli ze-biopharma zinokuvula amandla apheleleyo ngamaqela abo, idatha yabo, kunye nemibhobho yabo.
Qaphela: Iphinde yafunyanwa kwi-biophaphadive. Ukuba kukho nakuphi na inkxalabo yelungelo lokushicilela, nceda uqhagamshelane neqela lewebhusayithi ukuze zisuswe.
IXESHA LOKUQALA: 2025 - 05 - 30 10:47:51
