Ka nako e fetileng - Ho fetolela lefatše la biotechnology, DNA e Plasmid DNA e hlahile e le sebapali sa ba bohlokoa, haholo-holo sebakeng sa kalafo ea sele. Ha sechaba sa bongaka se ntse se tsoela pele ho sutumelletsa meeli ea se ka khonehang, karolo ea pna e atlehileng le ts'ebetsong ea kalafo ea limmapa e ka se tsosoe. Sengoliloeng sena se fetela lefatšeng le rarahaneng la plasmid DNA, ho hlahloba bohlokoa ba eona, ts'ebetso ea ho etsa thepa le litlamorao tsa eona ho setseng sa sele. Re tla boela re hlahloba karolo ea libapali tsa bohlokoa indastering, e totobatsang menehelo ea bahlahisi ba Plasmid DNA ea Barekisi ba Plasmid - Barekisi le lifekthele. Qetellong, re tsebisa k'hamphani e etellang pele sebakeng sena,Bluekit, 'me u buisane ka hore na seo batho ba neng ba se bua ka botona bo qala joang bokamoso ba kalafo ea sele.
Ho utloisisa lefu la ho utloisisa
Plasmid dna ke eng?
Plasmid DNAe bua ka likotoana tse nyane tse chitja tse teng ho tloha ka ntle ho DNA tsa li-chromomal le lisele tse ling tsa Eukarytic. Hangata theko ea limolek'hule e pheta ka boiketsetso ebile hangata e sebelisoa e le lisele tseenjiniere ea liphatsa tsa lefutso ka lebaka la bokhoni ba bona ba ho tsamaea le liphatsa tsa lefutso tsa liphatsa tsa bona tsa lefutso. Theko e ikhethang ea DNA e etsa sesebelisoa sa bohlokoa tšimong ea biotechnology, haholo nts'etsopele ea mekhoa ea lefutso le liente.
Bohlokoa ba plasmid DNA ho biotechnology
DNA e plasmid e bapala karolo ea bohlokoa boenjiniere ba liphatsa tsa lefutsong, ho sebetsa e le koloi bakeng sa phetisetso ea liphallelo. Mekhoa ea eona ea ho pheta ka bolokolohi e lumella bafutelli hore ba hlahise bongata ba tatellano ea li-disque tse khethehileng tsa DNA, e ka tsebisoa ka lintho tse ling. Sena se sebetsa haholo ho tlhahiso ea liprotheine tse nkhōlisang, li theha lintho tsa bongaka tse fetotsoeng ka liphatsa tsa lefutso, le nts'etsopele ea liphekolo tsa TICECY.
Plasmid DNA ka har'a kalafo ea sele
Karolo ea Plasmid DNA ka The Cell Therapy
Phekolo ea Sell e kenyelletsa tsamaiso ea lisele tsa lisele tse phelang ho mokuli ho phekola kapa ho senya lefu. Ho hlahisoa ha DNA ea Plasmid ho ts'ebetsong ena ho fetolela tšimo, e lumella ho feto-fetoha ha lisele ho hlahisa liprotheine tse ikhethang tsa masela. Sena se ka ntlafatsa ts'ebetso ea kalafo ka maemo a fapa-fapaneng, ho kenyelletsa le mofets'e le khatello ea lefutso.
Likopo tsa Plasmid DNA ka The Cell Therapy
E 'ngoe ea likopo tse sa tsebehaleng ka ho fetisisa tsa DNA tsa Plasmid DNA ka koloi - T (Chimmeric Antigen seceptor, kalafo e hlophisitsoeng bakeng sa mefuta e itseng ea mofets'e. Ts'ebetsong ena, TS - Lisele li ntsha mokuli, ha a fetotsoe liphatsa tsa mofets'e, 'me li hlahisoa' meleng oa mokuli ho hlasela lisele tsa mokuli ho hlasela lisele tsa mokuli ho hlasela lisele tsa mokuli. Pheko ena e hlahang habonolo e bontšitse katleho ea bohlokoa ho ho phekola liofisiri tsa mali ebile e ntse e hlahlojoa bakeng sa mefuta e meng ea mofetše.
Melemo ea ho sebelisa DNA ka DNA ka The Cell Therapy
Ts'ebeliso ea DNA ea Plasmid DNA ea Therapy e fana ka melemo e 'maloa:
Phapang le katleho: DNAsmid DNA e ka tsamaisana le litaelo tse tobileng ea liphatsa tsa lefutso, e lumellang sepheo se nepahetseng.
Tšireletseho: Lijana ke Litsebi tsa mahala, ho bolelang hore ho bolelang hore ha ba kopane le bakuli ho ba bakuli.
Scala e loketseng: Tsamaiso ea liphallelo ea lefu la plasmid DNA e thehiloe, e thehiloe, e lumella tse kholo - tlhahiso ea lipapatso.
Mokhoa oa ho etsa lihlahisoa tsa plasmid DNA
Kakaretso ea tlhahiso ea plasmid DNA
Ho hlahisoa ha pherekano ea plasmid ho kenyelletsa mehato e mengata ea bohlokoa, e leng se seng sa bohlokoa ho netefatsa boleng le katleho ea sehlahisoa le katleho. Ts'ebetso ena hangata e kenyelletsa mekhahlelo e latelang:
1. Moralo oa Plasmid le Kaho: Bohato ba pele bo kenyelletsa ho rala batšoasi ba pele ba li-vecMid ka lintho tse tonanang tsa lefutso, ho kenyelletsa baphatlalatsi, matšoao a khekhe. Ha e se e etselitsoe, liponto tsena li hahiloe ka ho sebelisa mekhoa ea ho koala elseng.
2. Khoakhoe: Lipapali tse hahiloeng li hlahisoa lisele tsa bacmal tse rekisoang ba bacmaria, moo li phetoang nakong ea karohano ea sele. Mohato ona oa ho holisa o oa hlokahala bakeng sa ho hlahisa DNA e lekaneng ea plasmid DNA.
3. Tlhomatso: Hang ha palo e lakatsehang ea plasmid e fumaneha, e ntšoa le ho hloekisoa ho tloha liseleng tsa baktheria. Ts'ebetso ena e kenyelletsa ho tlosa litšila le litšila tsa cellular le litšila ho netefatsa bohloeki bo matla.
4. Taolo ea boleng: Mehato ea taolo ea boleng bo boima e kenngoa ho netefatsa botšepehi ba plasmid, ho nepahala ha ho nepahala ha ho nepahala le ho thetsa. Sena se tiisa hore DNA ea plasmid e kopana le litekanyetso tse hlokahalang bakeng sa ts'ebeliso ea kalafo.
Liphephetso ho la Plasmid DNA
Ha ke ntse ke beha litholoana tsa dna e tsamaisitsoe haholoanyane ha lilemo li ntse li feta, ha e na mathata. Lintho tse kang tlhahiso e ngata, 'me bohloeki le bohloeki ke likhopolo-taba ea bohlokoa tseo ba etsang qeto. Ntle le moo, ho rarahana ha moralo oa plasmid le tlhoko ea mehato ea taolo ea boleng bo holimo ho etsa hore ts'ebetso ena e khetheloe haholo.
Libapali tsa bohlokoa li ka indasteri ea DASMID DNA
Baeti ba Plasmid DNA, barekisi le lifeme
Tlhokahalo ea Plasmid indastering ea biopharmaceecy e lebisitse ho hlaha, bahlahisi ba bakang ba fanang ka lithupelo. Lintho tsena li bapala karolo ea bohlokoa ea ho netefatsa hore ho fumaneha ha Ple - DNA ea VASMID e boleng ba lipatlisiso le lits'ebetso tsa cliniki.
Baetsi ba Lihlahisoa tsa Plasmid: Mekhatlo ena e ikarabella bakeng sa ho hlahisa DASMID CNALES ka bongata bo fokolang le bo boholo. Ba na le boiphihlelo ba botekgesi le lits'ebeletso tse hlokahalang ho sebetsana le mekhoa ea boqapi ba plasmid, ho holisa le ho tlhoekiso.
Barekisi ba Plasmid DNA barekisi: Barekisi ba sehlopha sa libui, ba tsamaisa lihlahisoa tsa DNA ho etsa lipatlisiso, likhamphani tsa biotech le litsi tsa bongaka. Li netefatsa phepelo e tsitsitseng ea DNA e tsitsitseng ea DNA ea ho fihlela litlhoko tsa pheletso e fapaneng - basebelisi.
Lifetrol tsa Plasmid: Litoro tsa Litoro tsa Plasmid DNA li na le boemo ba Plasmid DNA Ba latela melao ea tlhahiso ea lihlahisoa ho netefatsa boleng bo phahameng ka ho fetisisa ba lihlahisoa tsa DNA tsa DNA.
Karolo ea plasmid DNA barekisi ka ho ba le barekisi ba sebakeng sa ho iphekola
Plasmid DNA Barekisi ba Bohlokoa ba Karolo ea Bohlokoa ba ho tsamaisa nts'etsopele le Khoebo ea Phekolo ea Liele. Ka ho fana ka Plasmoid DNA, e nolofatsa bafuputsi le baoki ba etsang lithuto tse fanoang le banna, ba potlakisa phetolelo ea li-fress tsa li-sturing.
Phetha: Bokamoso ba Plasmid DNA ka The Cell Therapy
Ha tšimo ea biotechnology e ntse e tsoela pele, bohlokoa ba pherekano ea plasmid DNA ka kalafo ea selefoui e tla hola feela. Ho fapana ha eona, polokeho, ho sebetsa hantle, ho sebetsa hantle ho etsa hore ke sesebelisoa sa bohlokoa sa ho nts'etsapele kalafo bakeng sa mafu a mangata. Phetohelo pakeng tsa bahlahisi ba Plasmid DNA ea Plasmid, barekisi le lifektheri ba bohlokoa ho fihlela tlhoko ea ho lekanya tlhokofatso e atlehileng ea kalafo ea lisele.
Kenyelletso ea Bluekit
Jiangsu Hi Hith Ka netweke e kholo ea litsi tsa li-gmp le R & d ho Shanghai, Hillgene ke moetapele oa tlhahiso-leseling ea selefouno. Lihlahisoa tsa bona tsa Bluekit li fana ka ho seha - Litharollo tsa taolo ea boleng, li ts'ehetsa nts'etsopele ea koloi - THE STEM Ikemisetsa ho sebetsana le khoebo ea liforomo tsa lingaka, Bluekit e ikemiselitse ho ntlafatsa tharollo ea mokuli ka tharollo ea botsebi ka biotechnology.
Nako ea poso: 2025 - 2025 - 03 - 28 11:09:05
