Nhungamidzo Yepashure DNA Kuedzwa
Kuongororwa kwasara DNA kunoreva nzira dzekuongorora dzinoshandiswa kuona uye kujekesa trace huwandu hweDNA iyo inoramba iripo muBiolfeka zvigadzirwa mushure mekugadzira maitiro. Rudzi urwu rwekuedzwa rwakakosha rwekuona kuchengetedzwa nekuchena kwezvinhu zvipenyu, zvinosanganisira masero ekurapa, kusendama, uye kurwisa antibodies. Kuvapo kweDRODIDAD DNA muBiopharmaceutals, kunyanya DNA kubva kumasero ekutambira seE..Cool, inoisa njodzi ingangoita inosanganisira immunogenicity uye tumorigenicity. Naizvozvo, nzvimbo dzakasimba dzeDNA yekuongororwa chikamu chakakosha chemhando yepamusoro yekudzora mu biopharmacarical kugadzirwa.
● Tsanangudzo uye kukosha
Kugara pasi peDND kuongororwa kunosanganisira kuongororwa uye kuiswa kwezvidimbu zveDNA zvakasiiwa kubva kumasero ehondo anoshandiswa panguva yekugadzirwa kwemabhuku ezvipenga. Izvi zvidimbu zvinogona kusiyana muhukuru uye huwandu, uye kunyange miniti mari inogona kuve yakakosha. Kukosha kwekuedzwa kweDND hakugone kuve kwakasarudzika - kunoona kuti biopharmaceuticals vanosangana nematanho ekudzora ekuchengetedza uye kushanda kwehutano hwemurwere.
● Shandisa mune zvemhando yepamusoro
Kudzora Kwemhando muBiopharmaceucal Kugadzirwa kunosanganisira matanho mazhinji, kubva pakurwiswa kwezvinhu zvekusimbisa kwekupedzisira kwekupedzisira kuongororwa. Reside DNA kuyedzwa idanho rakakosha mukati meiyi chimiro. Inosimbisa kuti maitiro ekuzvinatsa akanyatso bvumurwa geneted geneted geneted genetic
Basa reDRODUDAD DNA muBiophaMeuticals
● Mhando dzeBiophaMeuticals
Biopelmaceutals inokomberedza huwandu hwakawanda hwezvigadzirwa, kusanganisira monoclonal antibodies, mapuroteni ekudzorera, maccins, uye masero ekurapa. Chikamu chimwe nechimwe chine akasiyana maitiro ekugadzira, asi zvese zvinokanganiswa neDNEDIALD DNA kusvibiswa.
● zvinyorwa zve
Rasara Congother host cell masero anosanganisira masero ehutachiona seE.Coli, mbiriso yemasero, mamonal masero, uye masero ezvipembenene. Munguva yekugadzirwa kwe biopharmacicals, aya masero anonyara kukohwa chigadzirwa chaunoda, anogona kusunungura zvinhu zvavo genetsic mumusanganiswa.
Nheyo dzeTauqman Probe muDNA Details
● Chishandiso chekuita
Iyo Taqman probe - Yakavakirwa Assay is a wasers inonyatso kushandiswa nzira yeiyo yakasara DNA yekuwanikwa. Iyi nzira inoshandisa iyo fluorescently yakanyorwa probe iyo hybridize kune chaiyo DNA kutevedzana kwekufarira. Iyo Taq Polymerase enzyme yakazungunuka probe panguva yePCR org.nrescent dhayeti kubva kuQuencher uye kuburitsa chiratidzo chinowanikwa.
● Zvakanakira Taqman Probe
Chimwe chezvakanyanya zvakanakira taqman probe ndeyechokwadi. Iko kugona kwemubhadharo wekukuvadza kune yakasarudzika kutevedzana kunoita kuti chete iyo Inga Intanti DNA yakamisikidzwa uye yakaonekwa, kuderedza mapepa enhema. Iyi nzira zvakare inopa zvakare kukwirira kwepamusoro, ichiita kuti ive yakakodzera kuona yakaderera mazinga ekugara.
E E.Coli sechitokisi chebasa mu biopilluticals
● Nei e.acli inowanzoshandiswa
E.Coli is computer inofarira cell mu biotechnology nekuda kwekukura kwayo nekukurumidza, zvakanaka - Aya hunhu anogadzira e.acoli mutengo - Sarudzo uye inoshanda sarudzo yeakakura - kujaira kugadzirwa.
● Zvinorehwa nezvakasara e.cli
Kunyangwe zvakanakira, kushandiswa kweE. Iyi yakasara DNA inogona kuisa zvinetso zvekuchengetedza, zvakadai sekugona kwekutenderera gene kuendesa kana kuvapo kwe endotoxins. Naizvozvo, dzigadzi zvakasara nzira dzekuedzwa nzira dzakakosha kana uchishandisa E.Coli sekutambira kwekugadzira.
Nzira dzakawanda dzekuona
● Matekota anoshandiswa muhuwandu
Maitiro akati wandei anoshandirwa kuwanda kwekuonekwa kweDesitive DNA, inosanganisira QPCr, digital PCR, uye inotevera - kuyananiswa. Imwe neimwe nzira inopa zvakanakira zvakasiyana maererano nekunzwa, chokwadi, uye kubudikidza.
● Kunzwa uye kurongeka
Mukugara kwakasara kuongororwa kweDNA, kunzwa uye kurongeka kwakarongeka. Maitiro akadai saQPCr uye digital PCR anogona kuona DNA at femartim Kunyatso kukosha kwakaenzana, sezvo inovimbisa kuvimbika kwemiedzo yemiedzo, kubvumira chisarudzo chivimbo - kugadzira mukudzora kwemhando.
Kukosha kwe fg level kuona
● Tsanangudzo yeFG Level
Iyo fg level inoreva fighotogromoons, chikamu cheyero chinomiririra 10 ^ - 15 magiramu. Detector DNA kuFemhotograph level inoratidza yakanyanya kuterera inokwanisa kuongororwa kuongororwa huwandu hwezvinyorwa zvemberi.
● Kukosha kwekunzwa kwepamusoro
Sensitivity yekunzwa muELLIDUAL DNA yekuongororwa inokosha yekuona kuchengetedzeka kwe biophaceuticals. Detecting DNA kuFG Level inobvumira kuzivikanwa kweiyo conthints dzakatemerwa, kuona kuti chigadzirwa chekupedzisira chakachena sezvazvinogona uye zvinosangana nematanho ekugadzirisa maitiro.
Mhando dzekudzora matanho mu biopharmaceutical kugadzirwa
● Kuda kwekupedzisira DNA kuyedzwa
Iko kudikanwa kwekuseri kweDNA kuongororwa muBiopharmaceutical kugadzirwa kunobva kune angangoita njodzi dzinoenderana nekukasira genetic. Magaro ekuzvidzora ekuzvidza anomanikidza miganhu yakasimba pane yakasara DNA maneja, inokoshesa nzira dzakayedzwa dzekuyedza kuti uve nechokwadi chekuteverera.
● Maitiro ekudzora
Zvitupa zvekudzokorora zveDzerial DNA vary zvichienderana nerudzi rwe biolmaceutical. Semuenzaniso, FDA uye Ema akagadza nhungamiro inotsanangudza zvinogamuchirika miganhu yeDNA yeDNA mune zvakasiyana zvigadzirwa. Kuomerera kune izvi zviyero zvakakosha pakubvumidzwa kwechigadzirwa uye kusunungurwa kwemusika.
Zvikumbiro muProteinant protein kugadzirwa
● Nhanho yeChie Nhaurwa
MuProtein protein kugadzirwa, kuongororwa kwakasara DNA kwakakosha kuti uve nechokwadi chekuchena kwechigadzirwa. Zvakananga kesi zvidzidzo zvinoratidza kushandiswa kwakabudirira kweE.Coli Dna Resarague KitS yekutarisa uye kudzora DNA emazinga ekusvibisa, kuona kutevedzera zviyero zvekudzora.
● Chivimbiso chemhando
Vimbiso yemhando yepamusoro muProtein Preverin Production inosanganisira akawanda marongero ekuedzwa uye kusimbiswa. Kuongororwa kwasara DNA kunoita basa rinokosha mune iyi maitiro, kupa iyo data inodiwa kuratidza kuti maitiro ekuzvinatsa akanyatso bvisa genetic conamints.
Zvinonetsa muKusarwa DNA Kuedzwa
● Zvinetso zvehunyanzvi
Chimwe chezvinetso chepamusoro muKusarwa kweDNA testing ndiko kuoma kwehunyanzvi hwekuona uye kujekesa mwero wakaderera eDNA. Zvinhu zvakaita seSampu Matrix, Kujeka kweDNA, uye Assay Inhibition inogona kuomesa maitiro ekuedza.
● Kukunda zvipingamupinyi zvakajairika
Kukurira zvipingamupinyi izvi kunoda kushandiswa kwezviitiko zvepamberi uye zvakarongeka protocol. Vagadziri uye vanopa e-eecoli Dna nguva refu nguva yekugara vachinatsa zvigadzirwa zvavo, kusimudzira kunzwa uye chokwadi kusangana nezvinodiwa neindasitiri.
Renguva yemberi maitiro mune yakasara DNA kuyedzwa
● Kufambira mberi Kwenyika
Kufambira mberi kwehunyanzvi kwakagadzirirwa kuchinja nguva dzakasara dzeDNA. Nzvimbo dzakadai saCrispr - Stagess, Dhijitari PCR, uye Inotevera - Chizvarwa Chemumbozha Chinopa nzira itsva dzeDNA yakanangana neDNAD DNA.
● nzira dzinobuda uye zvishandiso
Anobuda mafambiro uye zvishandiso muzvisikwa zvakasara DOA yekuongororwa vimbiso yekuvandudza kurongeka uye kushanda kwemhando yekudzora kwemhando. Kufambira mberi uku kunogonesa biopharmaceutical vagadziri kuti vasangane nehuremu hwekudzora zviyero zvichironga kuchengeteka kwechigadzirwa.
Mhedziso
Residaal DNA kuongororwa chinhu chakakosha chikamu chemhando yekudzora mu biolpharmacarical kugadzirwa. Kuonekwa uye kuwanda kwekutarisa huwandu hweDNA kwakakosha kuti uve nechokwadi chekuchengetedza uye kushanda kwezvinhu zvakasikwa. Maitiro epamberi senge iyo Taqman Probe inopa kunzwa kwekunzwa uye chokwadi chinodiwa kusangana nemataurire ekutonga. Sezvo indasitiri inoenderera mberi nekuchinja, kuongororwa kwakasara nguva yekuongororwa kwakasiyana kuchaita basa rakakosha mukuchengetedza huwandu hwepamusoro hwehunhu hwechigadzirwa.
● NezveBluekit
Jiangsu Hillgege, pasi pechiratidzo zita rebluekit, akasimbisa misoro yake muSuzhou aine 10,000㎡ gmp zvidyarwa uye r & d pakati. Nesiti dzekugadzira muShenzen, Shanghai, uye saiti itsva iri kuvakwa kuNorth Carolina, Hondo iri kuwedzera kuvapo kwakawanda. Iyo kambani inokatyamadza mukuvandudzwa kwemhando yekudzora kwemasero yeCellular zvigadzirwa, vatsigiri vekodzero mukubudirira kwekubudirira kwemotokari - T, tCr - t, uye stem cell - zvigadzirwa. Bluekit yakazvipira kufambira mberi cell kurapa hunyanzvi uye kupa mhinduro dzakazvitsaurirwa dzemasero ekurapa zvigadzirwa.
Kutumira nguva: 2024 - 09 - 23 14:17:04
