Intangiriro Kuri Gukoporora nimero yo kumenya
Mu bihe byose - Guhura nubutaka bwubushakashatsi bwa genetike, gusobanukirwa nimero ya pome yahindutse imfuruka yibitekerezo byombi byo gusuzuma no kuvura. Akamaro ko Gukoporora nimero ya Gene itandukanijwe (CNVS) ntigishobora kwiyongera, kuko ari ngombwa mu kwiga indwara za genetique, gutera imbere kwa kanseri, ndetse n'imikorere ya generapies ya gene. Mu bice byinshi by'inyungu, gene ya RCL na VSVG gene igaragara ku ruhare rwabo mu nzira ya selile na virusi itera imanza, kimwe. Iyi ngingo ihitana mwisi ya nimero ya gene, yibanda ku nzoreshya nkaweGene Wandukure numerona selile yo kuvura serivise ya gene numero ya numero, byose byazanwe nayoboye gene wa kopi ya ruganda.
Tekinoroji yateye imbere mubushakashatsi bwa genetike
Uruhare rwa QPCR muri Rata
Umubare ntarengwa Polymeyese reaction (QPCR) yagaragaye nkigikoresho cyingenzi mu rwego rwo gukoporora nimero ya Gene. Ubu buhanga butuma bikoroshya neza no guhuza ADN bikurikirana, bigatuma ari byiza gutahura CNVs. Mu rwego rwo kuvura gene, aho gutanga neza no kwerekana ingirabuzimafatizo za therapeutic ni premount, QPCR - Uburyo bushingiye bwo gutanga ubusobanuro butagereranywa no kwiringirwa.
Guhanga udushya mubisobanuro bya vector
Kugaruka kwa ventivil yahinduye imivumo ya gene ya gene, itanga uburyo bwiza bwo gutanga ibikoresho bya geneti mu tugari. Aba baganga, akenshi bafite gene ya vsvg, barinjiye mu buryo bwo kwanduza no gutuza. Kwishyira hamwe kwa Kopi ya Kopi ya Runes yatejena mumisaruro ya vector itanga umusaruro wa gene yagenzuwe neza, uburyo bwo kuvura butanga.
Incamake ya RCL (VSVG) ya kopi ya gene numero
● Ibiranga n'inyungu zaBluekitIbicuruzwa
RCL (VSVG) ya kopi ya Gene nimero ya Bluekit yerekana iterambere rikomeye mu kwisuzumisha genetique. Yagenewe gusobanurwa neza, itanga uburyo bwihuse kandi bwuzuye bwo gukoporora nimero ya Gene, kugaburira ibikenewe byombi nubuvuzi. Porotokole yazo n'umukoresha - Igishushanyo cya Gicuti kikabigire igikoresho kitagereranywa kuri laboratoire kwisi yose.
● Ibice by'ingenzi n'imikorere
Ku mutima wibicuruzwa byubururu ni urutonde rwuzuye rwibikoresho no kugenzura, kugirango birebe imikorere ikomeye. Igikoresho kirimo umurongo usanzwe wa calibrated, wemerera abashakashatsi kugera kumwanya muto nimbaraga nke. Nka nimero ya Gene ya Gene ya Gutanga, Ubwenge bushimangira ubuziranenge kandi bwizewe mubitambo byibicuruzwa.
Fluorescent Probe na Mecr ya PCR
Ibisobanuro bya tekinike ya fluorescent
Ubuhanga bwa Fluorescent Flebe bwabaye ibipimo bya zahabu muri GAANDA. Mugukoresha ibizamini byanditseho fluorescence ku nvamisi ku ntego, ubwo buhanga butanga ibyiyumvo byinshi kandi byihariye, bifatika, bifatika ku buryo bwo gutahura cnvs.
● Ibyiza bya PCRBX MCR muburyo bwa genetike
PCRx PCR yongera imikorere yicyiciro cya genetike yemerera icyarimwe kwimyambaro yintego nyinshi muburyo bumwe. Ibi ntibigumana gusa ibimenyetso byicyitegererezo gusa ahubwo binagabanya igihe nigiciro bifitanye isano no gusesengura genetique, bigatuma habaho guhitamo amafaranga yatoranijwe muri Gesiyete ya Konsere.
Gusaba mubushakashatsi busanzwe
Gukoresha muri kanseri no mu myigire ya genetike
Gukoporora nimero ya gene itandukanye bigira uruhare runini mubikorwa bya kanseri zitandukanye hamwe nibibazo bya genetique. Ibikoresho nkibikoresho bya selile Genda numero bigira uruhare runini mukumenya itandukaniro, bituma kwivuza byihariye no kuzamura umusaruro wihanga.
● Ingaruka za virusi ya virusi
Muri viral Vector umusaruro, kubuza nimero ya SE GOUT ni ngombwa kubikorwa bya TheRapeutic n'umutekano. Imikoreshereze ya kopi ya Gero Mool muriyi nzira iremeza ko abaganga bakorerwa hamwe na moderi yifuzwa, batezimbere ubushobozi bwabo bwo kuvura.
Ibisobanuro no gukora neza muri diagnostique ya genetike
Akamaro k'ukuri muri REC
Ukuri muri RECAPING nibyingenzi mubushakashatsi hamwe nubuvuzi. Amakosa muri Gene Dosage arashobora kuganisha ku gusuzuma cyangwa kuvura bidakora neza. Ibisobanuro byatanzwe na Kopi ya Koporo ya Geronomvy, nk'abo baturutse Bludikit, byemeza ko isesengura rya genetique byombi byizewe kandi bikarangwa.
● Ukuntu iyi myitozo irengera ibisubizo byimbere
Binyuze mu gishushanyo mbonera cy'ibitekerezo no kwipimisha, Gene ya Bluekit nimero ya kopi yo gutanga ibizagurika. Buri kikoresho cyakozwe kugirango ugabanye impinduka kandi zigabanye neza, gushiraho urwego rwa kopi ya Gene nimero ya Kit Kit kwisi yose.
Umukoresha - Igishushanyo cya gicuti na protocole
Kurohereza uburyo bwo kugerageza genetike
Ibyingenzi byo kugerageza genetike akenshi bitanga ibibazo kubashakashatsi. Bluekit akemura ibi nibicuruzwa bitagabanijwe gusa - impande gusa ariko nabyo birashoboka. Porotokone zabo zorohereza uburyo bwo kwipimisha, kwemerera abashakashatsi kwibanda kuri gusobanura ibisubizo aho kuba bakemura ibibazo.
● Igihe - Kuzigama ibintu byubururu
Igihe cyo gukora igihe ni kiranga nimero ya Bluekit Gelowe. Mu kugabanya umubare wintambwe no gushiramo kwitegura - Kuri - Koresha Reagents, ibi bikoresho bizigama umwanya numutungo wingenzi, bikaba ukunda muri kopi ya gene nimero ya ruganda.
Igisubizo cyuzuye hamwe numurongo usanzwe
Inyungu zo kugira umurongo wubatswe - umurongo usanzwe
Yubatswe - mumirongo isanzwe ni ikintu cyingenzi gishyiraho ibicuruzwa bya bluekit bitandukanye. Iremeza uko bihamye hakurya hakurya, bigabanya ubushobozi bwikosa ryabantu no kuzamura ubwizenguzi bwibisubizo.
Kugabanya ikosa ryabantu hamwe na presuction - gushiraho
Pre - gushiraho umubare wibipimo bivuze ko abakoresha bamara umwanya muto wo guhamya ubushakashatsi hamwe nigihe kinini cyibanda ku gusobanura amakuru. Uku kugabanya ikosa ryabantu ni ngombwa mu gukomeza isesengura ryisesengura rya genetike.
Ubushakashatsi bwakozwe nukuri - Porogaramu yisi
Ingero zubushakashatsi bwiza ukoresheje ibikoresho
Ubushakashatsi bwinshi bwubushakashatsi bwakoresheje neza ibicuruzwa byubururu kugirango ateze imbere imyumvire yabo ya kopi ya Gene. Kurugero, ubushakashatsi bwa kanseri buherutse gukorwa bwakoresheje ibi bikoresho kugirango tumenye CNV zikomeye zijyanye no kwigitarurira gutera imbere no kurwanya kuvura.
● Ubuhamya bwubuhamya buva kuringaniza generale
Abashakashatsi bakomeye mu murima bashimye nimero ya Genda ya Bane kuva Bluekit kubwubukwe bwabo, bworoshye bwo gukoresha, no kwizerwa. Iherezo nkiryo rishimangira umwanya wa kit 'umwanya nkumwanya wambere muri reko ya kopi ya gene nimero yabakora.
Icyerekezo kizaza muri RO PROP SERIGHSESSE
Iterambere rishobora guteza imbere genetike
Kazoza k'ibizamini bya genetike biri mu kwishyira hamwe kwikoranabuhanga rihanitse n'uburyo. Mugihe umurima uhindagurika, bluekit witeguye kuyobora ikirego, guteza imbere ibisubizo bishya bisunika imipaka ishoboka musesengura nimero ya gene.
● Uburyo ibisubizo bya Bluekit bishobora guteza ubushakashatsi buzaza
Ubwitange bw'Ubururu bwo guhanga udushya butuma bukomeza ko ikomeza ku isonga ry'ubushakashatsi bwa genetike. Mugukomeza gutunganya numero ya kopi ya gene ya Gene, batanga abashakashatsi bafite ibikoresho bikenewe kugirango bafungure ibyabumbuzi bushya bya siyansi hamwe ninteruro ya therapeutic.
Ibyerekeye Bluekit
Jiangsu Hillgene, akorera munsi yikirango bluekit, afite icyicaro muri Suzhou hamwe nibihingwa bya GMP hamwe na R & D Centre. Birata imbuga zo gukora muri Shenzhen na Shanghai, hamwe no kubaho biri imbere muri Carolina y'Amajyaruguru, muri Amerika. Ubururu bwubururu mu rubuga rwo guteza imbere ibicuruzwa bitesha umutwe, gushyigikira imodoka - T, TCR - T, na Stem Trovations. Ubwitange bwabo kuri kugenzura ubuziranenge no kuvura ibicuruzwa bitera imbere kubayobozi mu murima, bitanze guteza imbere ibyiyumvo bya selile ku nyungu z'indwara z'isi.
Igihe cyagenwe: 2025 - 02 - 28:58:06
