Ntchito za CDMO kwa vetikir - Kalasi ya malonda
Lentivirus, subype wa retrovirus, imatha kuphatikiza majini a chandamale mu masenti omwe ali pachiwopsezo, ndipo nthawi zambiri amagwiritsidwa ntchito ngati veral verring encriner urlering. Ndi kutuluka kwa makompyuta othandizira ma cell, zomwe zimapangitsa kuti ma vectore a Lentivil a Lentiviral akuwonjezekanso chaka chilichonse. Mapiri ali ndi mwayi pakukonzekera kwa CDMO yophatikizira za ma cell othandizira ma cell roral rarum -
Ntchito
* Dziwani: Timapereka kusintha kosinthika ndi kusinthasintha kwa ntchito, kuphatikiza koma osangokhala pa ntchito.
Ubwino
Kupanga
Kuwongolera kwapadera
* Dziwani: Mapiri okhazikitsidwa qc ofananira ndi nsanja zosiyana zaukadaulo, ndi njira za QC kuphatikiza koma osangokhala pamwamba pa zinthu.
Project Projekine
Dongosolo Loyang'anira Ntchito
Gulu la Phill Hillgene
Ntchito
| Ntchito za CDMO ya Ventivil Vectors (Hilenti® Pulatifomu) | ||||
| Mitundu | Ntchito | |||
| Kalasi ya malonda | 1 | GMP wopanga ma vetikiyi a lentivisiral |
● Bireactor: 5 ~ 50 l kutayika njira ya bioreactor (malinga ndi kusintha kwachilengedwe) ● Gawo lopanga: 2 ~ 30 l (malinga ndi kusintha kwachilengedwe) |
/ |
Ubwino
| Ubwino Wosintha nsanja yathu ya seramu - Kuyimitsidwa Kwaulere Kuyesedwa kwa Ma vectors a Lentivisi:
• wopanda nyama - zopangidwa ndi zomwe zimapangidwa munthawi yonseyi • Kupanga molingana ndi ma vetivisi Kugwiritsa ntchito chidebe chimodzi cha 50 l • Cet Cet Bank mu Zolemba Zosakaniza • Kuyika zinthu zomaliza pogwiritsa ntchito indolator yosalala • Makina odzipereka a Lentivirus agalimoto - T maselo, okhala ndi mphamvu yayikulu • Ndalama zochepa zopanga ndi ndalama zoyeserera (palibe zofunikira pakuyesa BSA ndi zotsalira pancreatic michere) • Kutumiza kopambana komwe kumayenderana ndi mipata ya ventivisi ya lentivisi yagalimoto - T |
Kupanga
Kuwongolera kwapadera
| Chinthu | Chiyeso | Njira Yoyesera |
| Kukolola madzi | Kuipitsidwa kwa kachilombo kodetsa | Njira 3302 ya chip 2020 |
| Kubwezera - Lentitent Lentiirses | Njira yachizindikiro ya cell | |
| Zogulitsa / Zomalizidwa | Kaonekedwe | Kuyang'ana Zowoneka |
| Kusamutsa | Njira 1101 ya Chip 2020 | |
| Mycoplasma |
Njira 3301 ya Chip 2020 |
|
| pH | Njira 0631 ya Chip 2020 | |
| Oswelality | Njira 0632 ya Chip 2020 | |
| Chidziwitso cha Get Center | Kusazidza | |
| Zotsalira zotsalira za protein | Elia | |
| Ngwazi yakuthupi (P24) | Elia | |
| Zogwirira Chake | Kutulutsa cytometry | |
| Endottoxin | Njira 1143 ya Chip 2020 | |
| Zotsalira benzonase | Elia | |
| Zotsalira za cell DNA | Q - PCR | |
| Kusamutsa kwa E1a Genes | CO - Njira Chikhalidwe | |
| Kutumiza kwa SV40 | CO - Njira Chikhalidwe |
Project Projekine
Dongosolo Loyang'anira Ntchito
Gulu la Phill Hillgene
